COMPANY ANNOUNCEMENTS
Brain+ A/S appoints Anders Härfstrand as new Chairman of the Board
Company Announcement Monday, September 5, 2022, 10:00 CET The information communicated in this announcement is “inside information” for the purposes of article 7 of the Market Abuse Regulation 596/2014 Brain + A/S (“Brain+”) today announced Anders Härfstrand, who was elected to the board of directors at the company’s Extraordinary General Meeting on September 2, 2022, has been appointed new Chairman of the Board. Anders Härfstrand has extensive international life science industry and leadership experience, and succeeds Lars Terney, who continues on the board as Vice Chairman after having served as Chairman for the past year.[ ]
Brain+ announces results of Extraordinary General Meeting of Shareholders
Copenhagen, Denmark – 2 September 2022 – Brain+ A/S (“Brain+”) [BRAINP], today announced the results of the Extraordinary General Meeting of Shareholders of Brain+ (“EGM”) which was held on 2 September 2022.
Brain+ A/S intends to add three international life science profiles as new board members in a strategic move ahead of its near-term commercial launch
Monday, August 8, 2022, 8:30 CET The Board of Directors of Brain+ A/S (“Brain+”) hereby notifies of its intention to convene an Extraordinary General Meeting (“EGM”) on Friday, September 2, 2022. The purpose of the EGM is the election of three new board members, nominated as candidates by the Board of Directors: Anders Härfstrand, Chairman of Diurnal Group, Johan Luthman, EVP & Head of R&D at Lundbeck, and Betül Susamis Unaran, Member of the Board of Directors of Ypsomed. The candidates represent a valuable span of international competencies of high relevance for Brain+’s near-term move into commercialization and subsequent business expansion.
Notice of Extraordinary General Meeting of Brain+ A/S
The shareholders of Brain+ A/S are hereby invited to attend an Extraordinary General Meeting on Friday 2[nd] September 2022 at 09:00 (CEST). The Extraordinary General Meeting will take place at Købmagergade 53, 3. 1150 Copenhagen as a physical event.
Minutes of the Annual General Meeting 2022 in Brain+ A/S
On Wednesday 18th of May at 14:00 CET Brain+ A/S held its Annual General Meeting at Hauser Pl. 20, 5., 1127 København.
Notice of Annual General Meeting of Brain+ A/S and Change to the Board of Directors
Invitation to Annual General Meeting The shareholders of Brain+ A/S are hereby invited to attend the Annual General Meeting scheduled for 18th May 2022, 14:00. The general meeting will be take place at Hauser Pl. 20, 5., 1127 København as a physical event.
Annual Report 2021 for Brain+ A/S
Brain+ annual report for 2021 is now available on the Company´s website
Positive results from the first of four clinical studies to evaluate Brain+’ Starry Night cognitive test for early detection of Alzheimer’s Disease
BRAIN+ A/S (BRAINP) Company Announcement No. 2-2022 Thursday, February 3., 2022, 09:00 CET The information communicated in this announcement is “inside information” for the purposes of article 7 of the Market Abuse Regulation 596/2014
Brain+ A/S (BRAINP) appoints Chief Financial Officer
BRAIN+ A/S (BRAINP) Company Announcement No. [1-2022] [Thursday January 27, 2022, 17:00 CET]
Brain+ lands first large-pharma partnership deal to enter the German market for dementia products
BRAIN+ A/S (BRAINP) Company Announcement No. 4-2021 Wednesday, December 15, 2021, 8:20 CET The information communicated in this announcement is “inside information” for the purposes of article 7 of the Market Abuse Regulation 596/2014 Brain+ has signed a partnership agreement with RoX Health (https://roxhealth.com/), a subsidiary of the global pharma company Roche in Germany, to bring its first dementia products to the German market.
Board member announces intention to leave board
BRAIN+ A/S (BRAINP) Company Announcement No. 3-2021 Tuesday November 16, 2021, 22:05 CET
Brain+ IPO 169% subscribed by 1,288 investors
The total subscription in the IPO was DKK 25.4 million from a total of 1,288 subscribers, translating into a subscription percentage of 169% counting all shares offered in the offering.
Danish Digital Medicine Company Brain+ Goes Public
THURSDAY, SEP 16, 2021 Brain+ A/S is offering Units and has applied for admission to trading on Nasdaq First North Growth Market Denmark.
INVESTOR NEWS
Brain+’ new digital product for dementia, “CST–Therapist Companion” is ready for commercial launch in Denmark in Q4 2022 – one year ahead of plan
BRAIN+ A/S (BRAINP) · The Brain+ “CST-Therapist Companion” is a new digital product to deliver Cognitive Stimulation Therapy (CST), a globally recognized evidence-based non-pharmaceutical dementia therapy · The Danish market for the Brain+ digital CST products, of which CST-Therapist Companion is the first, is estimated at € 30 million · CST is used in 35 countries today, and Brain+ is the first to offer a digital version of the therapy
Brain+ is experiencing growing interest from big pharma in its Digital Therapeutics solutions for dementia
Brain+ is a first mover in the field of Digital Therapeutics (DTx) solutions to treat Alzheimer’s Disease (AD) and other types of dementia and help relieve the growing burden of these conditions on patients, relatives, and societies. According to the World Health Organization, currently, more than 55 million people live with dementia worldwide, and there are nearly 10 million new cases every year.
Common Nordic digital health evaluation framework launched
Digital Therapeutics (DTx) is a growing trend and is increasingly a recognized market providing an important supplement to the established trillion USD pharmaceutical market (traditional medicine). The DTx trend is evolving fast. In June 2022 the Nordic Digital Health and Evaluation Criteria (NordDEC) program has been created. The NordDEC is a world-first program to unify digital health standards across multiple countries, delivering safe digital health across Sweden, Denmark, Norway, Finland, and Iceland.
Germany opens the DiPA reimbursement pathway to support the adoption of digital health applications, underpinning the value of the #1 target market for Brain+’ first commercial dementia product, CST
· A significant event for Brain+ as DiPA can provide reimbursement coverage for the first Cognitive Stimulation Therapy (CST) product, expected to be launched in Germany in 2023 · The CST product fits well with the requirements of the DiPA reimbursement pathway. The goal of the DIPA is to reimburse products that stabilize patients' health with special training programs or facilitates communication with family members and nursing care professionals, and this is the same purpose as the product. · The DIPA pathway can thus enable access to the Brain+ CST products for the 1 million Germans living with mild-to-moderate dementia, which is the target segment for the CST products.
1m SEK FORTE grant project to map state of the art digital interventions for dementia begins, helping Brain+ to strengthen patient and caregiver compliance for product development
· PURPOSE: The FORTE project will perform a scoping review of digital interventions for dementia and mild cognitive impairment and engage with live user panels to map out the state-of-the-art in the field. Brain+ focus is to strengthen knowledge on caregiver compliance for product development. Caregiver compliance impacts patient health outcomes and makes the Brain+ digital Cognitive Stimulation Therapy (CST) products scalable. · Brain+ PRODUCT RELEVANCE: The Brain+ dementia treatment product, Cognitive Stimulation Therapy (CST) – Home Extension, which is the 2[nd] product in the CST product line. The product relies on a caregiver to interact with the person with dementia when the CST therapy is done at home. This is not an issue when CST is done in a clinic, which is the case for the 1[st] product CST – Therapist Companion, where the therapy is led by a trained CST professional.
Summary from Annual Report 2021: Brain+ (BRAINP) is ahead of its IPO plan
“We are dedicated to helping people with dementia and Alzheimer’s disease – their families and their caregivers – through the use of our unique Digital Therapeutic software solutions that are being developed and validated through rigorous scientific and clinical trials. 2021 brought us closer to this core objective and we are now in a strong position to launch our first dementia product in 2023, 2 years ahead of plan. This will be a highly important commercial first step towards leadership in an emerging US billion-dollar market”, said Kim Baden-Kristensen, CEO of Brain+.
Brain+ CTO unfolds the Company’s Technology Platform Strategy
Paula Petcu joined Brain+ as new Chief Technology Officer after the company’s IPO in 2021, and is now driving forth the company’s product development work and technology platform initiatives. She came from Lundbeck A/S, a pioneering pharma company within central nervous system (CNS) disorders, where she built up the digital health organization. In this article, she explains the Brain+ platform strategy and technology stack. Summary highlights · Platform strategy: We are building a technology platform that is both modular, scalable, configurable, and regulatory compliant, while also allowing for high-quality data collection and easy integration with other apps and platforms. · Technology Stack: Our therapeutic software solutions are developed for both web and mobile applications using Flutter, which is a worldwide recognized framework for building multi-platform applications from a single codebase. We build on a German-based cloud infrastructure to ensure compliance with German and European data privacy requirements. And we use a microservices architecture for the flexibility and modularity of our products.
Brain+ selected as ‘digital showcase for Denmark’ by Digital Hub Denmark
Brain+ has been selected as showcase in the HealthTech category, among other top cutting-edge start-ups from Denmark, who are leading the digital transformation of society. The selection of Brain+ is motivated by the company’s achievements and commitment to make effective dementia and Alzheimer’s treatments available to everyone, as digital medicine.
The Danish Foreign Ministry to promote Brain+ into elderly care homes in Germany – Europe’s largest Alzheimer’s market
Brain+ has been identified by the Danish Foreign Ministry as a high potential Danish medtech company relevant for the German market. Therefore, Brain+ has been invited into the Danish-German Care Alliance (Dänisch-Deutsche Pflegeallianz), which aims to put Danish medical technologies directly into the hands of relevant large German customers. In practice, this means that Brain+ will get the opportunity to engage in a structured series of workshops with six large care home chains during 2022 with the aim of establishing local pilots and lead customers for the product launch in 2023.
Brain+ and Biogen preparing for commercialization in Germany, the #1 EU market for digital therapeutics
Brain+ has been selected to Biogen’s and EIT Health’s exclusive Neurotech-prize program. This will give additional momentum to the preparations for launch of Brain+’s first dementia product on the German market in 2023. The German market is a global ‘reference’ market for Digital Therapeutics (DTx) products and succeeding here creates a strong base for global expansion.
Publication of results from an earlier study that showed cognitive improvements in people with Brain Injury after training with Brain+ Recover Computerized Cognitive Training product
BRAIN+ A/S Investor update · Critical, early validation of Brain+ Computerized Cognitive Training technology as effective on specific cognitive outcomes relevant for patients with dementia · Cognitive problems are primary symptoms in pre-stages of dementia and often caused by Alzheimer’s disease · Insights from this study have been built into both the design of Brain+’ new dementia product, Cognitive Stimulation Therapy, and the next generation of cognitive training Brain+ is devoloping to target pre-stages of dementia in Alzheimer’s patients
Known data from a pilot study that tested an early version the Brain+ Computerized Cognitive Training technology in Parkinson’s Disease has been published
BRAIN+ A/S Investor update · Feasibility of use by Parkinson’s patients was shown · Valuable information gained about patient compliance that is relevant for the products Brain+ is developing for Alzheimer’s and dementia · Insights from the study have been built into the Computerized Cognitive Training technology, which is currently being tested in people at risk of dementia, and from which results are expected later this year
Year End Update on Business Activities and Outlook
BRAIN+ A/S (BRAINP) Wednesday, December 29, 2021, 9:00 CET Investor update
2 months after IPO update
BRAIN+ A/S (BRAINP) Monday, December 13, 2021, 9:30 CET
Annual General Meeting
18.05.2022
Invitation to Annual General Meeting, Brain+ A/S
Registration Form, Annual General Meeting, Brain+ A/S
Proxy Form, Annual General Meeting, Brain+ A/S
Appendix 1 – Description of Board candidates
Notice of Annual General Meeting of Brain+ A/S and Change to the Board of Directors
Extraordinary General Meeting
02.09.2022
Invitation to Extraordinary General Meeting, Brain+ A/S
Registration Form, Extraordinary General Meeting, Brain+ A/S
Proxy and Postal Form, Extraordinary General Meeting, Brain+ A/S
Company Announcement, Brain+ Intends to Add Three New Board Members
Appendix 1 – Description of Board candidates